Ester M. Hammond: search on Z-Library

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1

Design, synthesis and evaluation of molecularly targeted hypoxia-activated prodrugs

O'Connor, Liam J, Cazares-Körner, Cindy, Saha, Jaideep, Evans, Charles N G, Stratford, Michael R L, Hammond, Ester M, Conway, Stuart J

Journal:

Nature Protocols

Year:

2016

Language:

english

File:

PDF, 644 KB

english, 2016

2

Ultra-High Dose Rate (FLASH) Radiotherapy: Silver Bullet or Fool's Gold?

Wilson, Joseph D., Hammond, Ester M., Higgins, Geoff S., Petersson, Kristoffer

Journal:

Frontiers in Oncology

Year:

2020

Language:

english

File:

PDF, 619 KB

english, 2020

3

Efficient synthesis of 2-nitroimidazole derivatives and the bioreductive clinical candidate Evofosfamide (TH-302)

O'Connor, Liam J., Cazares-Körner, Cindy, Saha, Jaideep, Evans, Charles N. G., Stratford, Michael R. L., Hammond, Ester M., Conway, Stuart J.

Journal:

Organic Chemistry Frontiers

Year:

2015

Language:

english

File:

PDF, 1.13 MB

english, 2015

4

News and Short Contributions

Norman Hammond, Michael Ester, Anna Benjamin and S. Alan Skinner

Journal:

Journal of Field Archaeology

Year:

1978

Language:

english

File:

PDF, 1.31 MB

english, 1978

5

[Advances in Experimental Medicine and Biology] Tumor Microenvironment Volume 899 || Isolation of Mouse and Human Tumor-Associated Macrophages

Koumenis, Constantinos, Coussens, Lisa M., Giaccia, Amato, Hammond, Ester

Year:

2016

Language:

english

File:

PDF, 662 KB

english, 2016

6

[Advances in Experimental Medicine and Biology] Tumor Microenvironment and Cellular Stress Volume 772 || The Role of Complement in Tumor Growth

Koumenis, Constantinos, Hammond, Ester, Giaccia, Amato

Year:

2014

Language:

english

File:

PDF, 756 KB

english, 2014

7

[Advances in Experimental Medicine and Biology] Tumor Microenvironment Volume 899 || Isolation of Glioma-Initiating Cells for Biological Study

Koumenis, Constantinos, Coussens, Lisa M., Giaccia, Amato, Hammond, Ester

Year:

2016

Language:

english

File:

PDF, 513 KB

english, 2016

8

[Advances in Experimental Medicine and Biology] Tumor Microenvironment Volume 899 || Quantification of Lung Metastases from In Vivo Mouse Models

Koumenis, Constantinos, Coussens, Lisa M., Giaccia, Amato, Hammond, Ester

Year:

2016

Language:

english

File:

PDF, 562 KB

english, 2016

9

[Advances in Experimental Medicine and Biology] Tumor Microenvironment and Cellular Stress Volume 772 || Hypoxia and Metabolism in Cancer

Koumenis, Constantinos, Hammond, Ester, Giaccia, Amato

Year:

2014

Language:

english

File:

PDF, 694 KB

english, 2014

10

Hypoxia Potentiates the Radiation-Sensitizing Effect of Olaparib in Human Non–Small Cell Lung Cancer Xenografts by Contextual Synthetic Lethality

Jiang, Yanyan, Verbiest, Tom, Devery, Aoife M., Bokobza, Sivan M., Weber, Anika M., Leszczynska, Katarzyna B., Hammond, Ester M., Ryan, Anderson J.

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2016

Language:

english

File:

PDF, 2.67 MB

english, 2016

11

[Advances in Experimental Medicine and Biology] Tumor Microenvironment Volume 899 || Efficient Protocol for the Identification of Hypoxic Cell Radiosensitisers

Koumenis, Constantinos, Coussens, Lisa M., Giaccia, Amato, Hammond, Ester

Year:

2016

Language:

english

File:

PDF, 684 KB

english, 2016

12

WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer

Poujade, Flore-Anne, Mannion, Aarren, Brittain, Nicholas, Theodosi, Andrew, Beeby, Ellie, Leszczynska, Katarzyna B., Hammond, Ester M., Greenman, John, Cawthorne, Christopher, Pires, Isabel M.

Journal:

British Journal of Cancer

Year:

2018

Language:

english

File:

PDF, 1.43 MB

english, 2018

13

The roles of Chk 1 and Chk 2 in hypoxia and reoxygenation

Ester M. Hammond, Rachel A. Freiberg, Amato J. Giaccia

Journal:

Year:

2006

Language:

english

File:

PDF, 169 KB

english, 2006

14

Breaking up of prolonged sitting over three days sustains, but does not enhance, lowering of postprandial plasma glucose and insulin in overweight and obese adults

Larsen, Robyn N., Kingwell, Bronwyn A., Robinson, Carol, Hammond, Louise, Cerin, Ester, Shaw, Jonathan E., Healy, Genevieve N., Hamilton, Marc T., Owen, Neville, Dunstan, David W.

Journal:

Clinical Science

Year:

2015

Language:

english

File:

PDF, 616 KB

english, 2015

15

[Advances in Experimental Medicine and Biology] Tumor Microenvironment Volume 899 || Staining Against Phospho-H2AX (γ-H2AX) as a Marker for DNA Damage and Genomic Instability in Cancer Tissues and Cells

Koumenis, Constantinos, Coussens, Lisa M., Giaccia, Amato, Hammond, Ester

Year:

2016

Language:

english

File:

PDF, 1.41 MB

english, 2016

16

Radiosensitisation in vivo by histone deacetylase inhibition with no increase in early normal tissue radiation toxicity

Groselj, Blaz, Ruan, Jia-Ling, Scott, Helen, Gorrill, Jessica, Nicholson, Judith, Kelly, Jacqueline, Anbalagan, Selvakumar, Thompson, James, Stratford, Michael RL, Jevons, Sarah J., Hammond, Ester M.,

Journal:

Molecular Cancer Therapeutics

Year:

2017

Language:

english

File:

PDF, 3.05 MB

english, 2017

17

The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality

Johnson, Thomas M, Hammond, Ester M, Giaccia, Amato, Attardi, Laura D

Journal:

Nature Genetics

Year:

2005

Language:

english

File:

PDF, 349 KB

english, 2005

18

The role of ATM and ATR in the cellular response to hypoxia and re-oxygenation

Ester M. Hammond, Amato J. Giaccia

Journal:

Year:

2004

Language:

english

File:

PDF, 229 KB

english, 2004

19

RASSF1A–LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2

Pefani, Dafni-Eleftheria, Latusek, Robert, Pires, Isabel, Grawenda, Anna M., Yee, Karen S., Hamilton, Garth, van der Weyden, Louise, Esashi, Fumiko, Hammond, Ester M., O’Neill, Eric

Journal:

Nature Cell Biology

Year:

2014

Language:

english

File:

PDF, 2.92 MB

english, 2014

20

Hypoxia-activated small molecule-induced gene expression

Collins, Sarah L, Saha, Jaideep, Bouchez, Laure C., Hammond, Ester M, Conway, Stuart J.

Journal:

ACS Chemical Biology

Year:

2018

Language:

english

File:

PDF, 3.12 MB

english, 2018

21

Inhibition of CD4/CDK6 Enhances Radiosensitivity of HPV Negative Head and Neck Squamous Cell Carcinomas

Göttgens, Eva-Leonne, Bussink, Johan, Leszczynska, Katarzyna B., Peters, Hans, Span, Paul N., Hammond, Ester M.

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2019

Language:

english

File:

PDF, 2.22 MB

english, 2019

22

Radiosensitization of renal cell carcinoma in vitro through the induction of autophagy

Selvakumar Anbalagan, Isabel M. Pires, Christopher Blick, Mark A. Hill, David J.P. Ferguson, Denise A. Chan, Ester M. Hammond

Journal:

Radiotherapy and Oncology

Year:

2012

Language:

english

File:

PDF, 601 KB

english, 2012

23

[Advances in Experimental Medicine and Biology] Tumor Microenvironment and Cellular Stress Volume 772 ||

Koumenis, Constantinos, Hammond, Ester, Giaccia, Amato

Year:

2014

Language:

english

File:

PDF, 5.75 MB

english, 2014

24

[Advances in Experimental Medicine and Biology] Tumor Microenvironment and Cellular Stress Volume 772 || Autophagy and Cell Death to Target Cancer Cells: Exploiting Synthetic Lethality as Cancer Therapies

Koumenis, Constantinos, Hammond, Ester, Giaccia, Amato

Year:

2014

Language:

english

File:

PDF, 316 KB

english, 2014

25

[Advances in Experimental Medicine and Biology] Tumor Microenvironment Volume 899 || Methods: Using Three-Dimensional Culture (Spheroids) as an In Vitro Model of Tumour Hypoxia

Koumenis, Constantinos, Coussens, Lisa M., Giaccia, Amato, Hammond, Ester

Year:

2016

Language:

english

File:

PDF, 833 KB

english, 2016

26

Oxygen sensing and the DNA-damage response

Ester M Hammond, Muriel R Kaufmann, Amato J Giaccia

Journal:

Current Opinion in Cell Biology

Year:

2007

Language:

english

File:

PDF, 215 KB

english, 2007

27

Targeting ATR in DNA damage response and cancer therapeutics

Fokas, Emmanouil, Prevo, Remko, Hammond, Ester M., Brunner, Thomas B., McKenna, W. Gillies, Muschel, Ruth J.

Journal:

Cancer Treatment Reviews

Year:

2014

Language:

english

File:

PDF, 760 KB

english, 2014

28

Exposure to acute hypoxia induces a transient DNA damage response which includes Chk1 and TLK1

Pires, Isabel M., Bencokova, Zuzana, McGurk, Chris, Hammond, Ester M.

Journal:

Year:

2010

Language:

english

File:

PDF, 915 KB

english, 2010

29

[Advances in Experimental Medicine and Biology] Tumor Microenvironment Volume 899 || Mouse Models of Brain Metastasis for Unravelling Tumour Progression

Koumenis, Constantinos, Coussens, Lisa M., Giaccia, Amato, Hammond, Ester

Year:

2016

Language:

english

File:

PDF, 767 KB

english, 2016

30

Clinical advances of hypoxia-activated prodrugs in combination with radiotherapy

Mistry, Ishna N., Thomas, Matthew, Calder, Ewen D.D., Conway, Stuart J., Hammond, Ester M.

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2017

Language:

english

File:

PDF, 2.18 MB

english, 2017

31

A Functional Approach Reveals a Genetic and Physical Interaction between Ribonucleotide Reductase and CHK1 in Mammalian Cells

Taricani, Lorena, Shanahan, Frances, Malinao, Maria-Christina, Beaumont, Maribel, Parry, David, Hammond, Ester

Journal:

Year:

2014

Language:

english

File:

PDF, 1.04 MB

english, 2014

32

Replication stress drives constitutive activation of the DNA damage response and consequent radioresistance in glioblastoma cancer stem cells

Carruthers, Ross, Ahmed, Shafiq, Ramachandran, Shaliny, Hammond, Ester, Chalmers, Anthony

Journal:

Year:

2018

Language:

english

File:

PDF, 69 KB

english, 2018

33

AKT inhibition as a strategy for targeting hypoxic HPV-positive HNSCC

GÃ¶ttgens, Eva-Leonne, Bussink, Johan, Ansems, Marleen, Hammond, Ester M., Span, Paul N.

Journal:

Radiotherapy and Oncology

Year:

2020

File:

PDF, 1.31 MB

2020

34

CH-01 is a Hypoxia-Activated Prodrug That Sensitizes Cells to Hypoxia/Reoxygenation Through Inhibition of Chk1 and Aurora A

Cazares-Körner, Cindy, Pires, Isabel M., Swallow, I. Diane, Grayer, Samuel C., O’Connor, Liam J., Olcina, Monica M., Christlieb, Martin, Conway, Stuart J., Hammond, Ester M.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 2.02 MB

english, 2013

35

[Advances in Experimental Medicine and Biology] Tumor Microenvironment and Cellular Stress Volume 772 || Hypoxia and Regulation of Cancer Cell Stemness

Koumenis, Constantinos, Hammond, Ester, Giaccia, Amato

Year:

2014

Language:

english

File:

PDF, 187 KB

english, 2014

36

[Advances in Experimental Medicine and Biology] Tumor Microenvironment and Cellular Stress Volume 772 || miR-210: Fine-Tuning the Hypoxic Response

Koumenis, Constantinos, Hammond, Ester, Giaccia, Amato

Year:

2014

Language:

english

File:

PDF, 319 KB

english, 2014

37

Checking in on Hypoxia/Reoxygenation

Freiberg, Rachel A., Krieg, Adam J., Giaccia, Amato J., Hammond, Ester M.

Journal:

Year:

2006

Language:

english

File:

PDF, 300 KB

english, 2006

38

[Advances in Experimental Medicine and Biology] Tumor Microenvironment Volume 899 || Measuring DNA Replication in Hypoxic Conditions

Koumenis, Constantinos, Coussens, Lisa M., Giaccia, Amato, Hammond, Ester

Year:

2016

Language:

english

File:

PDF, 699 KB

english, 2016

39

Apoptosis-Specific Protein (ASP) Identified in Apoptotic Xenopus Thymus Tumor Cells

Horton, John, Milner, Anne, Horton, Trudy, Ritchie, Pamela, Gascoyne, Duncan, Hewson, Tim, Hammond, Ester, Gregory, Christopher, Grand, Roger

Journal:

Developmental Immunology

Year:

1998

Language:

english

File:

PDF, 5.45 MB

english, 1998

40

Hypoxia-activated pro-drugs of the KDAC inhibitor vorinostat (SAHA)

Calder, Ewen D.D., Skwarska, Anna, Sneddon, Deborah, Folkes, Lisa K., Mistry, Ishna N., Conway, Stuart J., Hammond, Ester M.

Journal:

Year:

2020

File:

PDF, 1.12 MB

2020

41

Specific cleavage of γ catenin by caspases during apoptosis

Katja Schmeiser, Ester M Hammond, Sally Roberts, Roger J.A Grand

Journal:

Year:

1998

Language:

english

File:

PDF, 1.28 MB

english, 1998

42

ATM activation in hypoxia - causes and consequences

Olcina, Monica M, Grand, Roger JA, Hammond, Ester M

Journal:

Molecular & Cellular Oncology

Year:

2014

Language:

english

File:

PDF, 617 KB

english, 2014

43

[Advances in Experimental Medicine and Biology] Tumor Microenvironment Volume 899 || A Multimodal Data Analysis Approach for Targeted Drug Discovery Involving Topological Data Analysis (TDA)

Koumenis, Constantinos, Coussens, Lisa M., Giaccia, Amato, Hammond, Ester

Year:

2016

Language:

english

File:

PDF, 785 KB

english, 2016

44

[Advances in Experimental Medicine and Biology] Tumor Microenvironment Volume 899 || In Vivo Interrogation of the Hypoxic Transcriptome of Solid Tumors: Optimizing Hypoxic Probe Labeling with Laser Capture Microdissection for Isolation of High-Quality RNA for Deep Sequencing Analysis

Koumenis, Constantinos, Coussens, Lisa M., Giaccia, Amato, Hammond, Ester

Year:

2016

Language:

english

File:

PDF, 503 KB

english, 2016

45

Comparison of hypoxia-induced replication arrest with hydroxyurea and aphidicolin-induced arrest

Ester M. Hammond, Susannah L. Green, Amato J. Giaccia

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2003

Language:

english

File:

PDF, 180 KB

english, 2003

46

Erratum: RASSF1A–LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2

Pefani, Dafni-Eleftheria, Latusek, Robert, Pires, Isabel, Grawenda, Anna M., Yee, Karen S., Hamilton, Garth, van der Weyden, Louise, Esashi, Fumiko, Hammond, Ester M., O'Neill, Eric

Journal:

Nature Cell Biology

Year:

2015

Language:

english

File:

PDF, 77 KB

english, 2015

47

WIP1 and senescence: Oxygen matters

Olcina, Monica M, Hammond, Ester M

Journal:

Year:

2014

Language:

english

File:

PDF, 420 KB

english, 2014

48

Mechanisms and consequences of ATMIN repression in hypoxic conditions: roles for p53 and HIF-1

Leszczynska, Katarzyna B., Göttgens, Eva-Leonne, Biasoli, Deborah, Olcina, Monica M., Ient, Jonathan, Anbalagan, Selvakumar, Bernhardt, Stephan, Giaccia, Amato J., Hammond, Ester M.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.00 MB

english, 2016

49

Impact of Wee1 inhibition on the hypoxia-induced DNA damage response

O’Brien, Eleanor M., Senra, Joana M., Anbalagan, Selvakumar, Hill, Mark A., Hammond, Ester M.

Journal:

Tumor Microenvironment and Therapy

Year:

2013

Language:

english

File:

PDF, 800 KB

english, 2013

50

The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia

Ashton, Thomas M., Fokas, Emmanouil, Kunz-Schughart, Leoni A., Folkes, Lisa K., Anbalagan, Selvakumar, Huether, Melanie, Kelly, Catherine J., Pirovano, Giacomo, Buffa, Francesca M., Hammond, Ester M.,

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 1.28 MB

english, 2016

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